6-OAU (GTPL5846) [CAS 83797-69-7] - ChemeGen-活性小分子-抑制剂-激动剂

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Anti-infection
Arenavirus
Bacterial
CMV
Enterovirus
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DNA/RNA Synthesis
Eukaryotic Initiation Factor (eIF)
G-quadruplex
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HDAC
HSP
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Adiponectin Receptor
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Protein Tyrosine Kinase/RTK
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Androgen Receptor
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Estrogen Receptor/ERR
Progesterone Receptor
Thyroid Hormone Receptor
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Inhibitory Antibodies
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ADC
Epigenetic Reader Dom

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6-OAU (GTPL5846) [CAS 83797-69-7]

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产品详情

Cat. No.：	C102592	CAS：	83797-69-7
Formula：	C12H21N3O2	MWt：	239.31
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Inflammation/Immunology
Target：	IC50 value: 105 nM [1] Target: GPR84 agonist	Description：	6-OAU (GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.

[1]. Suzuki M, et al. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem. 2013 Apr 12;288(15):10684-91.

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