Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) [CAS 828934-41-4] - ChemeGen-活性小分子-抑制剂-激动剂

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Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) [CAS 828934-41-4]

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Cat. No.：	C102116	CAS：	828934-41-4
Formula：	C15H18ClNaO4	MWt：	320.74
Purity：	>98%	Solubility：	H2O
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Metabolic Disease
Target：	CPT-1[1]	Description：	Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

1. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5.

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