信号通路
- Anti-infectionArenavirusBacterialCMVEnterovirusFilovirusFungalHBVHCVHIVHSVInfluenza VirusParasiteReverse TranscriptaseRSVSARS-CoVVirus Protease
- Antibody-drug Conjugate/ADC RelatedADC CytotoxinADC LinkerDrug-Linker Conjugates for ADCPROTAC-linker Conjugate for PAC
- ApoptosisApoptosisFKBPBcl-2 Familyc-MycCaspaseDAPKFerroptosisIAPMDM-2/p53PKDRIP kinaseSurvivinThymidylate SynthaseTNF Receptor
- AutophagyAutophagyLRRK2MitophagyULK
- Cell Cycle/DNA DamageAntifolateAPCATM/ATRAurora KinaseCasein KinaseCDKCheckpoint Kinase (Chk)CRISPR/Cas9DeubiquitinaseDNA Alkylator/CrosslinkerDNA-PKDNA/RNA SynthesisEukaryotic Initiation Factor (eIF)G-quadruplexHaspin KinaseHDACHSPIRE1KinesinLIM Kinase (LIMK)Microtubule/TubulinMps1Nucleoside Antimetabolite/Analogp97PAKPARPPERKPolo-like Kinase (PLK)PPARRAD51ROCKSirtuinSRPKTelomeraseTOPKTopoisomeraseWee1
- CytoskeletonArp2/3 ComplexDynaminGap Junction ProteinIntegrinKinesinMicrotubule/TubulinMps1MyosinPAK
- EpigeneticsAMPKAurora KinaseDNA MethyltransferaseEpigenetic Reader DomainHDACHistone AcetyltransferaseHistone DemethylaseHistone MethyltransferaseJAKMicroRNAPARPPKCProtein Arginine DeiminaseTAM ReceptorSirtuin
- GPCR/G Protein5-HT ReceptorAdenosine ReceptorAdenylate CyclaseAdiponectin ReceptorAdrenergic ReceptorAngiotensin ReceptorBombesin ReceptorBradykinin ReceptorCannabinoid ReceptorCaSRCCRCGRP ReceptorCholecystokinin ReceptorCRFRCXCRDopamine ReceptorEBI2/GPR183Endothelin ReceptorGHSRGlucagon ReceptorGlucocorticoid ReceptorGNRH ReceptorGPCR19GPR109AGPR119GPR120GPR139GPR40GPR55GPR84Guanylate CyclaseHistamine ReceptorImidazoline ReceptorLeukotriene ReceptorLPL ReceptormAChRMCHR1 (GPR24)Melanocortin ReceptorMelatonin ReceptormGluRMotilin ReceptorNeurokinin ReceptorNeuropeptide Y ReceptorNeurotensin ReceptorOpioid ReceptorOrexin Receptor (OX Receptor)Oxytocin ReceptorP2Y ReceptorProstaglandin ReceptorProtease-Activated Receptor (PAR)RasRGS ProteinSigma ReceptorSomatostatin ReceptorTSH ReceptorUrotensin ReceptorVasopressin Receptor
- Immunology/InflammationArginaseAryl Hydrocarbon ReceptorCCRComplement SystemCOXCXCRFLAPHistamine ReceptorIFNARInterleukin RelatedIRAKMyD88NO SynthaseNOD-like Receptor (NLR)PD-1/PD-L1PGE synthaseSalt-inducible Kinase (SIK)SPHKSTINGThrombopoietin ReceptorToll-like Receptor (TLR)CD73Reactive Oxygen SpeciesGalectin
- JAK/STAT SignalingEGFRJAKPimSTAT
- MAPK/ERK PathwayERKJNKKLFMAP3KMAP4KMAPKAPK2 (MK2)MEKMixed Lineage KinaseMNKp38 MAPKRafRibosomal S6 Kinase (RSK)
- Membrane Transporter/Ion ChannelATP SynthaseBCRPCalcium ChannelCFTRChloride ChannelCRAC ChannelCRM1EAAT2GABA ReceptorGlyTHCN ChanneliGluRMonoamine TransporterMonocarboxylate TransporterNa+/Ca2+ ExchangerNa+/HCO3- CotransporterNa+/K+ ATPasenAChRNKCCP-glycoproteinP2X ReceptorPotassium ChannelProton PumpSGLTSodium ChannelTRP ChannelURAT1
- Metabolic Enzyme/Protease15-PGDH5 alpha Reductase5-LipoxygenaseAcetyl-CoA CarboxylaseAcyltransferaseAdenosine DeaminaseAdenosine KinaseAldehyde Dehydrogenase (ALDH)Aldose ReductaseAminoacyl-tRNA SynthetaseAminopeptidaseAngiotensin-converting Enzyme (ACE)ArginaseATGLATP Citrate LyaseCarbonic AnhydraseCarboxypeptidaseCathepsinCETPCOMTCytochrome P450Dipeptidyl PeptidaseDopamine β-hydroxylaseDrug MetaboliteE1/E2/E3 EnzymeElastaseEndogenous MetaboliteEnolaseFAAHFABPFactor XaFarnesyl TransferaseFatty Acid Synthase (FAS)FXRGlucokinaseGSNORGutathione S-transferaseHCV ProteaseHexokinaseHIF/HIF Prolyl-HydroxylaseHIV IntegraseHIV ProteaseHMG-CoA Reductase (HMGCR)HSPIndoleamine 2,3-Dioxygenase (IDO)Isocitrate Dehydrogenase (IDH)Lactate DehydrogenaseLXRMAGLMineralocorticoid ReceptorMitochondrial MetabolismMMPNADPH OxidaseNamptNEDD8-activating EnzymeNeprilysinPAI-1PDHKPGC-1αPhosphatasePhosphodiesterase (PDE)PhospholipaseProcollagen C ProteinaseProteasomePyruvate KinaseRAR/RXRReninRORSer/Thr ProteaseSGKStearoyl-CoA Desaturase (SCD)ThrombinTryptophan HydroxylaseTyrosinaseXanthine OxidaseGlutaminaseGlutathione Peroxidase
- Neuronal Signaling5-HT ReceptorAChEAdenosine KinaseAmyloid-βBeta-secretaseCaMKCGRP ReceptorCOMTDopamine ReceptorDopamine TransporterFAAHGABA ReceptorGlyTiGluRImidazoline ReceptormAChRMelanocortin ReceptorMelatonin ReceptorMonoamine OxidasenAChRNeurokinin ReceptorOpioid ReceptorSerotonin Transporterγ-secretase
- NF-κBIKKKeap1-Nrf2MALT1NF-κB
- PI3K/Akt/mTORAktAMPKATM/ATRDNA-PKGSK-3MELKmTORPDK-1PI3KPI4KPIKfyvePTEN
- PROTACE3 Ligase Ligand-Linker ConjugateLigand for E3 LigasePROTACPROTAC LinkerPROTAC-linker Conjugate for PACLigand for Target Protein for PROTACSNIPERTarget Protein Ligand-Linker Conjugate
- Protein Tyrosine Kinase/RTKAck1ALKBcr-AblBMX KinaseBtkc-Fmsc-Kitc-Met/HGFRDiscoidin Domain ReceptorDYRKEGFREphrin ReceptorFAKFGFRFLT3IGF-1RInsulin ReceptorIRAKItkPDGFRPKAPyk2ROSSrcSykTAM ReceptorTrk ReceptorVEGFRRET
- Stem Cell/WntCasein KinaseERKGliGSK-3HedgehogHippo (MST)JAKNotchOct3/4PKAPorcupineROCKsFRP-1SmoSTATTGF-beta/SmadWntYAPβ-cateninγ-secretase
- TGF-beta/SmadPKCROCKTGF-beta/SmadTGF-β Receptor
- Vitamin D RelatedVD/VDR
- OthersAndrogen ReceptorAromataseEstrogen Receptor/ERRProgesterone ReceptorThyroid Hormone ReceptorOthers
- Inhibitory Antibodies
- Cytokines
- ADC
- Epigenetic Reader Dom
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