(E)-Cardamonin ((E)-Cardamomin; (E)-Alpinetin chalcone) [CAS 19309-14-9]

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产品详情

Cat. No.：	CN00204	Chinese Name：	小豆蔻明
CAS：	19309-14-9	Formula：	C16H14O4
MWt：	270.28	Purity：	>98%
Solubility：	DMSO	Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month
Research Area：	Neurological Disease	Target：	IC50: 454 nM (hTRPA1 cation channel)[1]
Description：	(E)-Cardamonin is an antagonist of hTRPA1 cation channel with an IC50 of 454 nM.

[1]. Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21(9). pii: E1145.‍

[2]. Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.

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