(1R,2R)-2-PCCA hydrochloride [CAS 1609563-71-4] - ChemeGen-活性小分子-抑制剂-激动剂

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(1R,2R)-2-PCCA hydrochloride [CAS 1609563-71-4]

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Cat. No.：	C104323	CAS：	1609563-71-4
Formula：	C30H39Cl2N3O	MWt：	528.56
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months; -20°C 1 month	Research Area：	Neurological Disease
Target：	EC50: 3 nM (GPR88 receptor)	Description：	(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM.

[1]. Bi, Yingzhi, et al. Modulators of G Protein-Coupled Receptor 88. US 20110251204 A1.‍

[2]. Jin C, et al. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies. ACS Chem Neurosci. 2016 Oct 19;7(10):1418-1432.

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