(R)-(-)-Rolipram ((R)-Rolipram;(-)-Rolipram) [CAS 85416-75-7] - ChemeGen-活性小分子-抑制剂-激动剂

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(R)-(-)-Rolipram ((R)-Rolipram;(-)-Rolipram) [CAS 85416-75-7]

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产品详情

Cat. No.：	C101887	CAS：	85416-75-7
Formula：	C16H21NO3	MWt：	275.34
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Neurological Disease
Description：	(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

1. Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct 18;45(4):944.

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