(R)-Baclofen Hydrochloride (STX 209 hydrochloride) [CAS 63701-55-3] - ChemeGen-活性小分子-抑制剂-激动剂

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(R)-Baclofen Hydrochloride (STX 209 hydrochloride) [CAS 63701-55-3]

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产品详情

Cat. No.：	C105516	Chinese Name：	(R)-巴氯芬盐酸盐
CAS：	63701-55-3	Formula：	C10H13Cl2NO2
MWt：	250.12	Purity：	>98%
Solubility：	DMSO	Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months; -20°C 1 month
Research Area：	Neurological Disease	Target：	GABAB receptor[1]
Description：	(R)-Baclofen hydrochloride (STX-209 hydrochloride) is a derivative of gamma-aminobutyric acid (GABA) primarily used to treat spasticity and is in the early research stages for use for the treatment of

[1]. Mezler M, et al. Cloning and functional expression of GABA(B) receptors from Drosophila. Eur J Neurosci. 2001 Feb;13(3):477-86.‍

[2]. Henderson C, et al. Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. Sci Transl Med. 2012 Sep 19;4(152):152ra128.

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