(R)-BAY-85-8501 | ChemeGen

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(R)-BAY-85-8501 [CAS 2446175-39-7]

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Cat. No.：	C108755	CAS：	2446175-39-7
Formula：	C22H17F3N4O3S	MWt：	474.46
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months; -20°C 1 month	Research Area：	Others
Description：	(R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM.

[1]. Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.

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