(R)-ADX-47273 [CAS 851881-59-9] - ChemeGen-活性小分子-抑制剂-激动剂

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(R)-ADX-47273 [CAS 851881-59-9]

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产品详情

Cat. No.：	C106361	CAS：	851881-59-9
Formula：	C20H17F2N3O2	MWt：	369.36
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Neurological Disease
Target：	mGlu5：168 nM (EC50)	Description：	(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .

[1]. Engers DW, et al. Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. ChemMedChem. 2009 Apr;4(4):505-11.

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