Pertuzumab (Anti-Human HER2) [CAS 380610-27-5] - ChemeGen-活性小分子-抑制剂-激动剂

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Pertuzumab (Anti-Human HER2) [CAS 380610-27-5]

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产品详情

Cat. No.：	CA10009	Chinese Name：	帕妥株单抗
CAS：	380610-27-5	MWt：	145175.18
Purity：	>98%	Research Area：	Cancer
Target：	EGFR	Description：	Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.

[1]. Nahta R, et al. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survivalof breast cancer cells. Cancer Res. 2004 Apr 1;64(7):2343-6.

[2]. Scheuer W, et al. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Res. 2009 Dec 15;69(24):9330-6.

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