KM11060 [CAS 774549-97-2] - ChemeGen-活性小分子-抑制剂-激动剂

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Anti-infection
Arenavirus
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CMV
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Filovirus
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Apoptosis
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Bcl-2 Family
c-Myc
Caspase
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MDM-2/p53
PKD
RIP kinase
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TNF Receptor
Autophagy
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LRRK2
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ULK
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Antifolate
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ATM/ATR
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Casein Kinase
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CRISPR/Cas9
Deubiquitinase
DNA Alkylator/Crosslinker
DNA-PK
DNA/RNA Synthesis
Eukaryotic Initiation Factor (eIF)
G-quadruplex
Haspin Kinase
HDAC
HSP
IRE1
Kinesin
LIM Kinase (LIMK)
Microtubule/Tubulin
Mps1
Nucleoside Antimetabolite/Analog
p97
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Myosin
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TAM Receptor
Sirtuin
GPCR/G Protein
5-HT Receptor
Adenosine Receptor
Adenylate Cyclase
Adiponectin Receptor
Adrenergic Receptor
Angiotensin Receptor
Bombesin Receptor
Bradykinin Receptor
Cannabinoid Receptor
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EBI2/GPR183
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URAT1
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15-PGDH
5 alpha Reductase
5-Lipoxygenase
Acetyl-CoA Carboxylase
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Aldehyde Dehydrogenase (ALDH)
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Arginase
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HCV Protease
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NADPH Oxidase
Nampt
NEDD8-activating Enzyme
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PAI-1
PDHK
PGC-1α
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Phosphodiesterase (PDE)
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Procollagen C Proteinase
Proteasome
Pyruvate Kinase
RAR/RXR
Renin
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SGK
Stearoyl-CoA Desaturase (SCD)
Thrombin
Tryptophan Hydroxylase
Tyrosinase
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Glutaminase
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Neuronal Signaling
5-HT Receptor
AChE
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Amyloid-β
Beta-secretase
CaMK
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COMT
Dopamine Receptor
Dopamine Transporter
FAAH
GABA Receptor
GlyT
iGluR
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Monoamine Oxidase
nAChR
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γ-secretase
NF-κB
IKK
Keap1-Nrf2
MALT1
NF-κB
PI3K/Akt/mTOR
Akt
AMPK
ATM/ATR
DNA-PK
GSK-3
MELK
mTOR
PDK-1
PI3K
PI4K
PIKfyve
PTEN
PROTAC
E3 Ligase Ligand-Linker Conjugate
Ligand for E3 Ligase
PROTAC
PROTAC Linker
PROTAC-linker Conjugate for PAC
Ligand for Target Protein for PROTAC
SNIPER
Target Protein Ligand-Linker Conjugate
Protein Tyrosine Kinase/RTK
Ack1
ALK
Bcr-Abl
BMX Kinase
Btk
c-Fms
c-Kit
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Discoidin Domain Receptor
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IRAK
Itk
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RET
Stem Cell/Wnt
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ERK
Gli
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Hippo (MST)
JAK
Notch
Oct3/4
PKA
Porcupine
ROCK
sFRP-1
Smo
STAT
TGF-beta/Smad
Wnt
YAP
β-catenin
γ-secretase
TGF-beta/Smad
PKC
ROCK
TGF-beta/Smad
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VD/VDR
Others
Androgen Receptor
Aromatase
Estrogen Receptor/ERR
Progesterone Receptor
Thyroid Hormone Receptor
Others
Inhibitory Antibodies
Cytokines
ADC
Epigenetic Reader Dom

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KM11060 [CAS 774549-97-2]

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产品详情

Cat. No.：	C105736	CAS：	774549-97-2
Formula：	C19H17Cl2N3O2S	MWt：	422.33
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months; -20°C 1 month	Research Area：	Endocrinology
Description：	KM11060 is a novel corrector of the F508del-CFTR trafficking defect.

[1]. Robert R, et al. Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol. 2008 Feb;73(2):478-89.

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