(+)-JQ-1 (JQ1) [CAS 1268524-70-4] - ChemeGen-活性小分子-抑制剂-激动剂

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Anti-infection
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(+)-JQ-1 (JQ1) [CAS 1268524-70-4]

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产品详情

Cat. No.：	C101361	CAS：	1268524-70-4
Formula：	C23H25ClN4O2S	MWt：	456.99
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Cancer
Target：	IC50: 77/33 nM (BRD4(1/2))	Description：	(+)-JQ-1 is a BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)).

[1]. Filippakopoulos P, et al. Selective inhibition of BET bromodomains. Nature. 2010 Dec 23;468(7327):1067-73.

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