JNJ-10229570 [CAS 524923-88-4] - ChemeGen-活性小分子-抑制剂-激动剂

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Anti-infection
Arenavirus
Bacterial
CMV
Enterovirus
Filovirus
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Bcl-2 Family
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MDM-2/p53
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DNA/RNA Synthesis
Eukaryotic Initiation Factor (eIF)
G-quadruplex
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p97
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Ligand for Target Protein for PROTAC
SNIPER
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Protein Tyrosine Kinase/RTK
Ack1
ALK
Bcr-Abl
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c-Fms
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β-catenin
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Androgen Receptor
Aromatase
Estrogen Receptor/ERR
Progesterone Receptor
Thyroid Hormone Receptor
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Inhibitory Antibodies
Cytokines
ADC
Epigenetic Reader Dom

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JNJ-10229570 [CAS 524923-88-4]

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产品详情

Cat. No.：	C106016	CAS：	524923-88-4
Formula：	C22H19N3O2S	MWt：	389.47
Purity：	>98%	Solubility：	DMSO : 62.5 mg/mL (160.47 mM; Need ultrasonic)
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Endocrinology
Target：	IC50: 270 nM (human MC1R), 200 nM (human MC5R)	Description：	JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-1022

[1]. Eisinger M, et al. A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids. J Dermatol Sci. 2011 Jul;63(1):23-32.

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