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Corin [CAS 1808113-09-8]
Corin [CAS 1808113-09-8]
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产品详情
Cat. No.： C108174 CAS： 1808113-09-8
Formula： C26H28N4O2 MWt： 428.53
Purity： >98% Solubility： DMSO
Storage： 4°C, stored under nitrogen. In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) Research Area： Cancer
Target： IC50: 147 nM (HDAC1), Ki(inact): 110 nM (LSD1) Description： Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.

[1]. Kalin JH, et al. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nat Commun. 2018 Jan 4;9(1):53.
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