Cabergoline (FCE-21336) [CAS 81409-90-7] - ChemeGen-活性小分子-抑制剂-激动剂

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Cabergoline (FCE-21336) [CAS 81409-90-7]

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产品详情

Cat. No.：	C101677	Chinese Name：	卡麦角林
CAS：	81409-90-7	Formula：	C26H37N5O2
MWt：	451.60	Purity：	>98%
Solubility：	DMSO	Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month
Research Area：	Endocrinology	Target：	Ki: 0.7 (Dopamine D2 receptor), 1.5 (Dopamine D3 receptor), 1.2 (5-HT2B receptor)[1]
Description：	Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).

[1]. Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271.

[2]. Jefferson F, et al. A dopamine receptor d2type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.

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