2,4-Diamino-6-hydroxypyrimidine

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2,4-Diamino-6-hydroxypyrimidine [CAS 56-06-4]

Price：

￥400.00

Size：

500 mg

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产品详情

Cat. No.：	C107977	CAS：	56-06-4
Formula：	C4H6N4O	MWt：	126.12
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months;-20°C 1 month	Research Area：	Inflammation/Immunology
Target：	GTP cyclohydrolase I	Description：	2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production.

[1]. Sung YJ, et al. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol. 1994 Feb;16(2):101-8.

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