(24R)-MC 976 [CAS 112828-09-8] - ChemeGen-活性小分子-抑制剂-激动剂

信号通路

Anti-infection
Arenavirus
Bacterial
CMV
Enterovirus
Filovirus
Fungal
HBV
HCV
HIV
HSV
Influenza Virus
Parasite
Reverse Transcriptase
RSV
SARS-CoV
Virus Protease
Antibody-drug Conjugate/ADC Related
ADC Cytotoxin
ADC Linker
Drug-Linker Conjugates for ADC
PROTAC-linker Conjugate for PAC
Apoptosis
Apoptosis
FKBP
Bcl-2 Family
c-Myc
Caspase
DAPK
Ferroptosis
IAP
MDM-2/p53
PKD
RIP kinase
Survivin
Thymidylate Synthase
TNF Receptor
Autophagy
Autophagy
LRRK2
Mitophagy
ULK
Cell Cycle/DNA Damage
Antifolate
APC
ATM/ATR
Aurora Kinase
Casein Kinase
CDK
Checkpoint Kinase (Chk)
CRISPR/Cas9
Deubiquitinase
DNA Alkylator/Crosslinker
DNA-PK
DNA/RNA Synthesis
Eukaryotic Initiation Factor (eIF)
G-quadruplex
Haspin Kinase
HDAC
HSP
IRE1
Kinesin
LIM Kinase (LIMK)
Microtubule/Tubulin
Mps1
Nucleoside Antimetabolite/Analog
p97
PAK
PARP
PERK
Polo-like Kinase (PLK)
PPAR
RAD51
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Telomerase
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Wee1
Cytoskeleton
Arp2/3 Complex
Dynamin
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Integrin
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Microtubule/Tubulin
Mps1
Myosin
PAK
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AMPK
Aurora Kinase
DNA Methyltransferase
Epigenetic Reader Domain
HDAC
Histone Acetyltransferase
Histone Demethylase
Histone Methyltransferase
JAK
MicroRNA
PARP
PKC
Protein Arginine Deiminase
TAM Receptor
Sirtuin
GPCR/G Protein
5-HT Receptor
Adenosine Receptor
Adenylate Cyclase
Adiponectin Receptor
Adrenergic Receptor
Angiotensin Receptor
Bombesin Receptor
Bradykinin Receptor
Cannabinoid Receptor
CaSR
CCR
CGRP Receptor
Cholecystokinin Receptor
CRFR
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Dopamine Receptor
EBI2/GPR183
Endothelin Receptor
GHSR
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GNRH Receptor
GPCR19
GPR109A
GPR119
GPR120
GPR139
GPR40
GPR55
GPR84
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Histamine Receptor
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Leukotriene Receptor
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mAChR
MCHR1 (GPR24)
Melanocortin Receptor
Melatonin Receptor
mGluR
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PGE synthase
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EGFR
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iGluR
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nAChR
NKCC
P-glycoprotein
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Potassium Channel
Proton Pump
SGLT
Sodium Channel
TRP Channel
URAT1
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15-PGDH
5 alpha Reductase
5-Lipoxygenase
Acetyl-CoA Carboxylase
Acyltransferase
Adenosine Deaminase
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Aldehyde Dehydrogenase (ALDH)
Aldose Reductase
Aminoacyl-tRNA Synthetase
Aminopeptidase
Angiotensin-converting Enzyme (ACE)
Arginase
ATGL
ATP Citrate Lyase
Carbonic Anhydrase
Carboxypeptidase
Cathepsin
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COMT
Cytochrome P450
Dipeptidyl Peptidase
Dopamine β-hydroxylase
Drug Metabolite
E1/E2/E3 Enzyme
Elastase
Endogenous Metabolite
Enolase
FAAH
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Factor Xa
Farnesyl Transferase
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FXR
Glucokinase
GSNOR
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HCV Protease
Hexokinase
HIF/HIF Prolyl-Hydroxylase
HIV Integrase
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HMG-CoA Reductase (HMGCR)
HSP
Indoleamine 2,3-Dioxygenase (IDO)
Isocitrate Dehydrogenase (IDH)
Lactate Dehydrogenase
LXR
MAGL
Mineralocorticoid Receptor
Mitochondrial Metabolism
MMP
NADPH Oxidase
Nampt
NEDD8-activating Enzyme
Neprilysin
PAI-1
PDHK
PGC-1α
Phosphatase
Phosphodiesterase (PDE)
Phospholipase
Procollagen C Proteinase
Proteasome
Pyruvate Kinase
RAR/RXR
Renin
ROR
Ser/Thr Protease
SGK
Stearoyl-CoA Desaturase (SCD)
Thrombin
Tryptophan Hydroxylase
Tyrosinase
Xanthine Oxidase
Glutaminase
Glutathione Peroxidase
Neuronal Signaling
5-HT Receptor
AChE
Adenosine Kinase
Amyloid-β
Beta-secretase
CaMK
CGRP Receptor
COMT
Dopamine Receptor
Dopamine Transporter
FAAH
GABA Receptor
GlyT
iGluR
Imidazoline Receptor
mAChR
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Melatonin Receptor
Monoamine Oxidase
nAChR
Neurokinin Receptor
Opioid Receptor
Serotonin Transporter
γ-secretase
NF-κB
IKK
Keap1-Nrf2
MALT1
NF-κB
PI3K/Akt/mTOR
Akt
AMPK
ATM/ATR
DNA-PK
GSK-3
MELK
mTOR
PDK-1
PI3K
PI4K
PIKfyve
PTEN
PROTAC
E3 Ligase Ligand-Linker Conjugate
Ligand for E3 Ligase
PROTAC
PROTAC Linker
PROTAC-linker Conjugate for PAC
Ligand for Target Protein for PROTAC
SNIPER
Target Protein Ligand-Linker Conjugate
Protein Tyrosine Kinase/RTK
Ack1
ALK
Bcr-Abl
BMX Kinase
Btk
c-Fms
c-Kit
c-Met/HGFR
Discoidin Domain Receptor
DYRK
EGFR
Ephrin Receptor
FAK
FGFR
FLT3
IGF-1R
Insulin Receptor
IRAK
Itk
PDGFR
PKA
Pyk2
ROS
Src
Syk
TAM Receptor
Trk Receptor
VEGFR
RET
Stem Cell/Wnt
Casein Kinase
ERK
Gli
GSK-3
Hedgehog
Hippo (MST)
JAK
Notch
Oct3/4
PKA
Porcupine
ROCK
sFRP-1
Smo
STAT
TGF-beta/Smad
Wnt
YAP
β-catenin
γ-secretase
TGF-beta/Smad
PKC
ROCK
TGF-beta/Smad
TGF-β Receptor
Vitamin D Related
VD/VDR
Others
Androgen Receptor
Aromatase
Estrogen Receptor/ERR
Progesterone Receptor
Thyroid Hormone Receptor
Others
Inhibitory Antibodies
Cytokines
ADC
Epigenetic Reader Dom

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(24R)-MC 976 [CAS 112828-09-8]

Price：

￥10150.00

Size：

1 mg

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产品详情

Cat. No.：	C105322	CAS：	112828-09-8
Formula：	C27H42O3	MWt：	414.62
Purity：	>98%	Solubility：	DMSO
Storage：	Powder -20°C 3 years; 4°C 2 years In solvent -80°C 6 months; -20°C 1 month	Research Area：	Metabolic Disease
Target：	VD/VDR	Description：	(24R)-MC 976 is a Vitamin D3 derivative.

[1]. Strugnell S, et al. Metabolism of a cyclopropane ring-containing analog of 1α-hydroxyvitamin D3 in a hepatocyte cell model. Identification of 24-oxidized metabolites. Biochemical Pharmacology (1990), 40(2), 333-341.

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